![]() The enteric materials suitable for the present invention include those materials digestible by enzymes in the intestinal tract, enteric materials containing an ionizable polyacid, frequently a long-chain polymer with ionizable carboxyl groups, and the like. The materials and their degradation products should be physiologically inactive, the enteric materials should not dissolve or disintegrate in the stomach during the time the dispenser remains in the stomach, and the enteric materials should disintegrate once the dispenser enters the intestine. The enteric materials that can be blended with the semipermeable polymer for forming the wall of the dispenser are non-toxic enteric materials. A61M31/002- Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time.A61M31/00- Devices for introducing or retaining media, e.g.A61M- DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR.A61K9/0004- Osmotic delivery systems Sustained release driven by osmosis, thermal energy or gas.A61K9/0002- Galenical forms characterised by the drug release technique Application systems commanded by energy.A61K9/00- Medicinal preparations characterised by special physical form.A61K- PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES.A61- MEDICAL OR VETERINARY SCIENCE HYGIENE.Assignors: EDGREN, DAVID Application granted granted Critical Publication of US4522625A publication Critical patent/US4522625A/en Anticipated expiration legal-status Critical Status Expired - Lifetime legal-status Critical Current Links OF CA reassignment ALZA CORPORATION, A CORP. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Application filed by Alza Corp filed Critical Alza Corp Priority to US06/427,870 priority Critical patent/US4522625A/en Assigned to ALZA CORPORATION, A CORP. Original Assignee Alza Corp Priority date (The priority date is an assumption and is not a legal conclusion. ![]() Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Lifetime Application number US06/427,870 Inventor David Edgren Current Assignee (The listed assignees may be inaccurate. Google Patents Drug dispenser comprising wall formed of semipermeable member and enteric memberÄownload PDF Info Publication number US4522625A US4522625A US06/427,870 US42787082A US4522625A US 4522625 A US4522625 A US 4522625A US 42787082 A US42787082 A US 42787082A US 4522625 A US4522625 A US 4522625A Authority US United States Prior art keywords dispenser osmotic wall drug fluid Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents US4522625A - Drug dispenser comprising wall formed of semipermeable member and enteric member ![]() US4522625A - Drug dispenser comprising wall formed of semipermeable member and enteric member
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